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Optimisation of the development of poverty-related-diseases (PRD) vaccines by a transversal approach, addressing common gaps and challenges

The development of vaccines against poverty-related diseases faces several common gaps and challenges. These include difficulties in accessing know-how and technology platforms in vaccine development, formulation and delivery, difficulties in harmonising safety data collection, and an insufficient numbers of trained scientists able to undertake leadership roles in vaccine development.

INYVAX addresses these challenges by

  • Implementation of knowledge and technology resources for PRD vaccine developers and development of a common strategy across PRD vaccines

For both formulation work and adjuvant assessment this coordination action will develop tools and mechanisms to improve the sharing and the access to knowledge, know-how and information across PRD vaccine developers, in a very specific technical niche, which is largely “orphan” in both academic and biotech settings.

  • Improvement of the safety assessment of PRD vaccines

This action will increase awareness of Brighton safety standards among the project participants and stakeholders in international vaccine development and improve the applicability and “user-friendliness” of Brighton case definitions, data collection guidelines, and online tools. The  harmonisation of safety assessment during clinical trial will improve the comparability and allow meta-analysis of safety results  for a same type of vaccine formulation and/or different vaccines using same technologies or adjuvants.

  • Contribution to create a pool of trained and competent vaccine developers

INYVAX is sponsoring students of the Advanced Training Course in Vaccinology (ADVAC). This course provides a high level of interactions between people from different horizons, e.g. academia and industry. gathering immunologists, epidemiologists, pediatricians, public health experts or biotechnologists interested in vaccinology. It also offers the possibility for European scientists to establish contacts with other scientists from developing countries and favours North-South collaborations.

In addition a short training programme on optimisation of vaccines with adjuvants is being developed within this coordination action.

The project involves eight partner institutions and is funded by the European Commission's Framework Program 7 (FP7) as Coordination and Support Action, project number: 223532, with 932,335 €.

More details on the project can be found in the About section of this website.